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|Application:||Plant Growth Regulator,Plant Growth Hormone,Agriculture||State:||Powder,Liquid|
|Classification:||Plant Growth Regulator,Agrochemical / Pesticide,Biological Pesticide||Appearance:||White Powder,fine Powder,White Brown Liquid|
|Storage:||Dry Place,Sealed Tightly And Stored Away From Light In A Cool And Dry Place,Keep In Cool And Dry Place||Color:||White,white To Yellowish|
|Solubility:||Water,Soluble In Alcohol|
Cyanamide 50%SL Plant Growth Hormone,
Cyanamide 50%SL Synthetic Growth Hormone,
Cyanamide plant growth stimulation
Cyanamide is an organic compound with the formula CN2H2. This white solid is widely used in agriculture and the production of pharmaceuticals and other organic compounds. It is also used as an alcohol-deterrent drug in Canada, Europe, and Japan. The molecule features a nitrile group attached to an amino group. Derivatives of this compound are also referred to as cyanamides, the most common being calcium cyanamide (CaCN2).
Cyanamide can be regarded as a functional single carbon fragment which can react as an electrophile or nucleophile. The main reaction exhibited by cyanamide involves additions of compounds containing an acidic proton. Water, hydrogen sulfide, and hydrogen selenide react with cyanamide to give urea, thiourea, and selenourea, respectively: H2NCN + H2E → H2NC(E)NH2 (E = O, S, Se)
In this way, cyanamide behaves as a dehydration agent and thus can induce condensation reactions. Alcohols, thiols, and amines react analogously to give alkylisoureas, "pseudothioureas", and guanidines. The anti-ulcer drug cimetidine is generated using such reactivity. Related reactions exploit the bifunctionality of cyanamide to give heterocycles, and this latter reactivity is the basis of several pharmaceutical syntheses such as the aminopyrimidine imatinib) and agrichemicals Amitrol and hexazinone. The hair-loss treatment minoxidil and the anthelmintics albendazole, flubendazole, and mebendazole feature 2-aminoimidazole substructures derived from cyanamide. Cyanamide is also used in the synthesis of other pharmaceutical drugs including tirapazamine, etravirine, revaprazan, and dasantafil.
The cyanamide anion has the character of a pseudo chalcogen, cyanamide can therefore be regarded as analogue to water or hydrogen sulfide.
A convenient method for the preparation of secondary amines which are not contaminated with primary or tertiary amines is the reaction of cyanamide with alkyl halides to N,N-dialkylcyanamides which can easily be hydrolyzed to dialkylamines and then decarboxylated. Cyanamide adds itself in the presence of N-bromosuccinimide to olefinic double bonds. The addition product is converted by bases to N-Cyanaziridine, cyclized in the presence of acids to imidazolines, which can be further reacted to vicinal diamines by alkaline cleavage.
Cyanamide is also a versatile synthetic building block for heterocycles: it forms 2-aminobenzimidazole with 1,2-diaminobenzene and it forms with the readily available cyclic enamine 4-(1-cyclohexenyl)morpholine and with elemental sulfur a 2-aminothiazole in good yields.
Sodium dicyanamide is available in good yield and high purity from cyanamid and cyanogen chloride, which is suitable as an intermediate for the synthesis of active pharmaceutical ingredients. A guanidino group is introduced by reaction of cyanamide with sarcosine In the industrial synthesis of creatine:
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