Methoxyfenozide. Diacylhydrazine insecticide.
Ecdysone agonist that mimics the biological function of the natural insect molting hormone 20-hydroxyecdysone,
causing premature molting and interfering with the normal growth and development in insects.
Ecdysteroid agonist are also used as ligands for gene expression and gene therapy research.
Outlasting Residual Protection & Control of Lepidoptera Contains Methoxyfenozide,
the active ingredient used is an insect growth regulator that protects
almond, apple, peanut, citrus, and other crops from the feeding damage of Lepidopteran (moths, butterflies) insects.
Methoxyfenozide (CAS NO.161050-58-4) is diaryl hydrazine insect growth regulators, insecticides of
molting hormones,interfere with normal growth and development of insects and suppress feeding.
In particular, there are effects on the larvae and eggs.
Methoxyfenozide is an insect growth regulator (IGR) commonly used in agriculture to simultaneously control pests and preserve beneficial insect
populations; however, its impact on honey bees in not fully understood.
We conducted field and laboratory experiments to investigate bee health in response to field-relevant concentrations of this pesticide.
||98%TC, 24%SC, 240g/l SC
||3-methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
Oral Acute oral LD50 for rats 250-4150 (tech. 7180), mice 138 mg/kg.
Oral Acute oral LD50 for rats and mice >5000 mg/kg. Skin and eye Acute percutaneous LD50 for rats >5000 mg/kg. Not irritating to eyes; slightly irritating to skin (rabbits). Not a skin sensitiser (guinea pigs). Inhalation LC50 for rats >4.3 mg/l. NOEL (24 mo) for rats 10 mg/kg daily; (18 mo) for mice 1020 mg/kg daily; (1 y) for dogs 9.8 mg/kg daily. ADI 0.1 mg/kg (proposed). Other Negative in Ames test and a battery of other mutagenicity and genotoxicity studies. Toxicity class EPA (formulation) IV
||Mode of action Active primarily by ingestion, also with contact and ovicidal activity. Does not have translaminar or phloem-systemic properties. Uses Control of lepidopterous larvae, in vines, tree fruits, vegetables and row crops, at 20 - 300 g/ha.
||1L/Drum, 5L/Drum, 20L/Drun etc