CAS 106325 08 0 Epoxiconazole 12.5% SC Natural Plant Fungicide

                                                                                 Epoxiconazole

Epoxiconazole is a fungicide active ingredient from the class of azoles developed to protect crops.

In particular, the substance inhibits the metabolism of fungi cells infesting useful plants,

and thereby prevents the growth of the mycelia (fungal cells).

Epoxiconazole also limits the production of conidia (mitospores). Epoxiconazole  can be found in many products and product

mixtures targeting a large number of pathogens in various crops. Crops are, for example, cereals (mainly wheat, barley, rye and triticale),

soybeans, banana, rice, coffee, turnips, and red as well as sugar beets.

World food supply is projected to face additional stress in the future; within the next decade cereal demands in Europe alone are expected to

increase by 21%, while production is projected to increase by only 7%.  At the same time, two main cereal diseases, leaf blotch (Septoria tritici)

and rust (Puccinia triticina), are responsible for up to 30% yield losses. Failure to adequately control these diseases would affect both food

availability and food quality. Although not used commercially for insect control, epoxiconazole exhibits a strong anti-feeding effect on the keratin-

digesting common clothes moth larvae Tineola bisselliella.

As an azole, Epoxiconazole, actively stops the production of new fungi spores and inhibits the biosynthesis of existing hostile cells.

Epoxiconazole works as an eradicant by encapsulating fungal haustoria, which are then cut off from their nutrient supply and therefore die.

Some fungicide interactions can actually lead to increased production of mycotoxins, which are normal metabolic products of fungi,

and it has been found that the inclusion of triazoles, like Epoxiconazole, in the fungicide mix may be necessary to limit mycotoxin levels.

Active ingredient	Epoxiconazole
Classification	Fungicide / Agrochemical
Structural formula
Biochemistry	Inhibition of C-14-demethylase in sterol biosynthesis.
Mode of action	Preventive and curative fungicide.
Usage	Broad-spectrum fungicide, with preventive and curative action, for control of diseases caused by Ascomycetes, Basidiomycetes, and Deuteromycetes in cereals, sugar beet, peanuts, oilseed rape, and ornamentals, generally at 125 g/ha.
Mammalian Toxicology	Oral: Acute oral LD50 for rats >5000 mg/kg. Skin and eye: Acute percutaneous LD50 for rats >2000 mg/kg. Non-irritating to eyes and skin of rabbits. Inhalation: LC50 (4 h) for rats >5.3 mg/l air.