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|Other Names:||GALLEON||Cas No.:||99105-77-8|
Sulcotrione Organic Selective Herbicide,
98% TC Organic Selective Herbicide,
99105 77 8 Sulcotrione Powder
Mode of action studies with sulcotrione first led to the identity of HPPD as a highly effective herbicide target site. Early observations showed that a related compound caused increased levels of tyrosine in the plasma and urine of treated rats (12). Further studies showed that one of the tyrosine catabolism enzymes, 4-hydroxypyruvate dioxygenase, was inhibited by cyclohexanediones (13,14)—this enzyme being required for the formation of quinones, such as plastoquinone in plants (12,15,16). Inhibition results in the perturbation of carotenoid synthesis and inhibition of photosynthetic electron transport (16).
|Name of product||Sulcotrione|
|Synonyms||2-(2-Chloro-4-(methylsulfonyl)benzoyl)-1,3-cyclohexanedione; ICIA0051; SC0051|
|CAS Registry Number||99105-77-8|
|Applications||Biochemistry p-Hydroxyphenyl pyruvate dioxygenase inhibitor. Mode of action Herbicide, absorbed predominantly by the leaves, but also by the roots. Uses Control of broad-leaved weeds and grasses post-emergence in maize and sugar cane, at 200-300 g/ha. Formulation types SC. Selected tradenames: 'Galleon' (Syngenta, Bayer); 'Mikado' (Syngenta, Bayer)|
|Description||Oral Acute oral LD50 for rats >5000 mg/kg. Skin and eye Acute percutaneous LD50 for rabbits >4000 mg/kg. Low rate of absorption through the skin; non-irritating to skin; mild eye irritant (rabbits). Strong skin sensitiser (guinea pigs). Inhalation LC50 (4 h) >1.6 mg/l. NOEL (2 y) for rats 100 ppm (0.5 mg/kg b.w. daily). ADI 0.005 mg/kg. Other Non-teratogenic in rats and rabbits.
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