CAS 68085 85 8 2.5%EC Lambda Cyhalothrin Insecticide agrochemicals agricultural

                                                                              Lambda-cyhalothrin

Cyhalothrin is the ISO common name for an organic compound that, in specific isomeric forms, is used as a pesticide.

It is a pyrethroid, a class of synthetic insecticides that mimic the structure and properties of the naturally occurring insecticide pyrethrin

which is present in the flowers of Chrysanthemum cinerariifolium. 

Pyrethroids such as cyhalothrin are often preferred as an active ingredient in agricultural insecticides

because they are more cost-effective and longer acting than natural pyrethrins.

λ-and γ-cyhalothrin are now used to control insects and spider mites in crops including cotton, cereals, potatoes and vegetables

Pyrethroids, including cyhalothrin, disrupt the functioning of the nervous system in an organism.

They are fast-acting axonic excitotoxins, the toxic effects of which are mediated by preventing the closure of the voltage-gated sodium

channels in axonal membranes. The sodium channel is a membrane protein with a hydrophilic interior.

This interior is shaped precisely to allow sodium ions to pass through the membrane, enter the axon, and propagate an action potential.

The binding of the insecticide to the protein keeps the channels in their open state,

so the nerves cannot repolarize, thereby paralyzing the organism. 

One consequence of the mode of action is that cyhalothrin has useful knockdown properties.

That is, affected larvae rapidly cease feeding and may fall off the crop;

flying insects drop to the ground. Paralysis and death follows provided the insect has absorbed a sufficient dose.