CAS 79983 71 4 Hexaconazole 98%TC Natural Plant Fungicide

                                                                                       Hexaconazole 

Hexaconazole is a broad-spectrum systemic triazole fungicide used for the control of many fungi particularly Ascomycetes and

Basidiomycetes. Major consumption is in Asian countries and it is used mainly for the control of rice sheath blight in China, India, Vietnam, and

parts of East Asia. It is also used for control of diseases in various fruits and vegetables.

Hexaconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-

demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. It is fungicidal against the powdery mildews B.

graminis and S. cucurbitae on cucumber plants in a concentration-dependent manner and is curative against powdery mildew on barley

plants when used at a concentration of 6.7 mg/L.  It also inhibits growth of R. bataticola and S. rolfsii (ED50s = 6.35 and 1.27 mg/L, respectively).  Exogenous application of hexaconazole (15 mg/L) to M. chamomilla plants improves water, proline, and protein contents as

well as increases non-enzymatic and enzymatic antioxidant and apigenin-7-glucoside content during a water deficit stress tolerance

test. Hexaconazole inhibits the differentiation of mouse embryonic stem cells into cardiomyocytes (EC50 = 16.6 μM).  It also induces bone

morphological defects in mouse fetuses when administered to pregnant adult females during gestation.