Abamectin drug veterinary medicine agricultural insecticide factory in China

Abamectin is a mixture of avermectins containing avermectin B1a and avermectin B1b. These two components, B1a and B1b have very similar biological and toxicological properties. The avermectins are insecticidal or anthelmintic compounds derived from the soil bacterium Streptomyces avermitilis. Abamectin is used to control insect and mite pests of a range of agronomic, fruit, vegetable and ornamental crops and it is used by homeowners for control of fire ants. Abamectin acts on insects by interfering with neural and neuromuscular transmission. Abamectin attenuated ethanol-induced gastric ulceration. Chemical structure and effects on GABAARs and P2X4Rs receptor function play key roles in the ability of avermectin to reduce ethanol intake

Abamectin belongs to the family of avermectins, which are macrocyclic lactones produced by a soil
actinomycete, Streptomyces avermitilis. It is a broad-spectrum acaricide with additional insecticidal
action on a limited number of insects. The compound acts on insects by increasing the membrane
permeability to chloride ions, and it mainly stimulates the release of Ȗ-aminobutyric acid (GABA).
The affected arthropod becomes paralysed, stops feeding, and dies after a few days. It exerts contact
and stomach action, with limited plant systemic activity, but exhibits translaminar movement into
treated leaves. Abamectin is also used as an anthelmintic drug in veterinary medicine

Abamectin is an insecticide and antihelmenthic agent in the avermectin class and is very similar to ivermectin . Abamectin is a widely used agricultural pesticide against insects and mites . Human and veterinary uses include treatment of Onchocerca volvulus (the nematode causing river blindness) . The intoxication may cause coma, hypotension, and respiratory failure .